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By integrating microtranscriptomic, Limited Proteolysis-Small Molecule Mapping (LiP-SMap), and small molecule-protein interaction analysis, we find that uridine directly targets poly(rC)-binding protein 1 (PCBP1), thereby suppressing ferroptosis, maintaining mitochondrial function, alleviating oxidative damage, and ultimately improving the quality of aged oocytes

However, as the levels of MPO itself as well as the availability of appropriate substrates can vary widely within the organism and the particular sites of inflammation, the extent of damage generated by this enzyme often cannot be accurately predicted

Tumor and liver acetylcarnitine were normalized to tissue weight while ascites was normalized to volume

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Both RSC1 and RSC2 complexes are stimulated by the cohesin loader Two distinct RSC complexes exist in budding yeast, characterized by the presence of one of the two paralogous Rsc1 or Rsc2 subunits